Neuroterapia VS Terapias Convenconais - Comparativo

COMPARATIVE

Neurotherapy
VS Conventional Therapies

Depression

Depression significantly affects quality of life, causing mental and physical suffering. Compare the effectiveness of conventional treatments with our advanced neurological approaches.

General effectiveness of treatments
Conventional Treatment (Medication)
15%
27.5%
Average rates of remission and improvement of symptoms, with 1 to 4 stages of treatment
Complete remission
Significant improvement
Transcranial Magnetic Stimulation (TMS)
38%
71%
Average remission and symptom improvement rates with TMS, after just 1 full cycle of treatment
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
95%
Percentage of patients reporting significant side effects
Transcranial Magnetic Stimulation (TMS)
4%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
TMS (Conventional Post-Fault)
58%
Percentage of patients with significant improvement after failure of ≥2 conventional treatments
Significant improvement

Important

It is important to note that the improvements only relate to the direct symptoms of depression, and the patient's general clinical condition is disregarded. Side effects are disregarded from the improvement rates, as long as they don't prevent improvement in the symptoms of depression. Therapies such as EMT/TMS fulfil the need to treat the illness alongside the patient, rather than treating the illness to the detriment of their general well-being. This page contains relevant background information on Depression and the treatments offered. It is crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

Transcranial Magnetic Stimulation (TMS) uses focussed magnetic fields to stimulate specific areas of the brain associated with depression. This non-invasive treatment demonstrates superior efficacy compared to antidepressant drugs, especially in cases resistant to conventional treatments. TMS does not have the common side effects of medication, such as weight gain, sexual dysfunction or drowsiness.

Fast results

Many patients report the first improvements within the first few weeks of treatment, while medication can take 5-7 weeks.

Duration of Effect

The positive effects of TMS can last from 6 months to 1 year after treatment, with periodic maintenance sessions. In many cases, using psychotherapeutic approaches, it is possible to achieve complete remission of symptoms

Neuropathic Pain

Neuropathic pain results from lesions or dysfunctions in the nervous system and is often resistant to conventional painkillers. Compare the effectiveness of treatments.

General effectiveness of treatments
Conventional Treatment (Medication)
3%
19%
Average remission rates and ≥50% improvement in pain across all treatment stages
Complete remission
Significant improvement
Transcranial Direct Current Stimulation (tDCS)
3%
75%
Average remission rates and ≥50% improvement in pain after just 1 full cycle of tDCS
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
55%
Percentage of patients reporting significant side effects
Transcranial Direct Current Stimulation (tDCS)
2%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
tDCS (Conventional Post-Fault)
40%
Percentage of patients with significant pain improvement (≥50%) after failure of conventional treatments
Significant improvement

Important

It's worth noting that these statistics only consider improvements of more than 50% in the frequency and intensity of pain. Improvements of 20, 30, 40% are extremely relevant in the treatment of conditions such as Neuropathic Pain. This section contains relevant background information on Neuropathic Pain and the treatments presented. It is crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

Transcranial Direct Current Stimulation (tDCS) applies a low-intensity electric current to modulate neuronal activity in specific areas of the brain. This non-invasive treatment has been shown to significantly reduce neuropathic pain by adjusting the neural circuits involved in pain perception and processing, offering relief where conventional medications fail.

No Significant Side Effects

Unlike many neuropathic pain medications, tDCS does not cause sedation, addiction or liver toxicity.

Personalised treatment

Stimulation can be adjusted specifically to your type of neuropathic pain and location, maximising results.

Migraine

Migraines can be debilitating, significantly affecting quality of life. Compare the effectiveness of conventional treatments with our advanced neurological approaches.

General effectiveness of treatments
Conventional Treatment (Medication)
20%
45%
Average remission rates and reduction in the frequency of monthly episodes (≥50%) with preventive prophylactic medication.
Complete remission
Significant improvement
Transcranial Magnetic Stimulation (TMS)
27%
45%
Average remission rates and reduction in the frequency of monthly episodes (≥50%) after 1 full cycle of TMS
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
70%
Percentage of patients reporting significant side effects
Transcranial Magnetic Stimulation (TMS)
3%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
TMS (Conventional Post-Fault)
72%
Percentage of patients with a significant reduction (≥50%) in seizure frequency after failure of conventional prophylactic treatments
Significant improvement

Important

It's important to note that the data presented refers only to the reduction in the frequency of episodes (MMD). EMT/TMS also affects the intensity of the pain. This section contains relevant background information on Migraine and the treatments presented. It is crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

TMS for migraines focuses on brain areas involved in pain and migraine processes. This non-drug treatment has been shown to be effective in both the prevention and treatment of acute crises, reducing the frequency, intensity and duration of migraines in patients who do not respond to conventional treatments.

Frequency reduction

Patients report an average reduction of 45% in the frequency of migraines after a full course of treatment.

Long-term relief

Many patients maintain the benefits for 3-6 months after the end of the treatment cycle. In some cases, complete temporary remission of symptoms or even definitive remission is possible.

Fibromyalgia

Fibromyalgia is characterised by widespread pain and tenderness at multiple points in the body and is often resistant to conventional treatments.

General effectiveness of treatments
Conventional Treatment (Medication)
2%
22%
Average remission rates and significant improvement in pain (≥50%) after 6 months of drug treatment
Complete remission
Significant improvement
Combined Approach (TMS + tDCS)
2%
40%
Average remission rates and significant improvement in pain (≥50%) after combined protocol (TMS+tDCS)
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
80%
Percentage of patients reporting significant side effects
Combined Approach (TMS + tDCS)
4%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
Combined Approach (Conventional Post-Failure)
48%
Percentage of patients with significant improvement (≥50%) in pain, fatigue, sleep, after failure of conventional treatments
Significant improvement

Important

This section contains relevant background information on Fibromyalgia and the treatments presented. It is crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

The combined approach of TMS and tDCS aims to modulate pain pathways and improve damaged sensory processing in fibromyalgia. This specific protocol shows superior results to conventional drugs, reducing generalised pain, improving sleep quality and reducing the fatigue associated with fibromyalgia.

Comprehensive Relief

The treatment not only reduces pain, but also improves other symptoms such as fatigue, sleep disturbances and mental clarity.

Reducing the Use of Medicines

More than 70% of patients manage to reduce their pain medication very significantly after treatment.

Insomnia

Chronic insomnia profoundly affects physical and mental health, contributing to the development of various conditions and reducing quality of life.

General effectiveness of treatments
Conventional Treatment (Medication)
28%
60%
Percentage of patients with complete normalisation or significant improvement in sleep pattern after 3 months of medication
Complete remission
Significant improvement
Transcranial Magnetic Stimulation (TMS)
35%
70%
Percentage of patients with complete normalisation or significant improvement in sleep pattern after complete TMS cycle
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
77%
Percentage of patients reporting significant side effects
Transcranial Magnetic Stimulation (TMS)
1%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
TMS (Conventional Post-Fault)
69%
Percentage of patients with normalised sleep pattern after medication failure
Significant improvement

Important

It's important to note that the treatment of Insomnia brings with it a determining factor - the risk of addiction. Neurotherapy solves this problem. The intensive and prolonged use of sleep drugs has severe consequences that should be avoided. This section contains relevant background information on Insomnia and the treatments presented. It is crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

TMS acts on the brain regions responsible for controlling sleep and circadian rhythm. This non-drug treatment normalises altered brain activity patterns in patients with insomnia, improving both sleep quality and total time slept, without the side effects and risks of dependence associated with hypnotic drugs.

Improved Sleep Quality

Patients report not only more sleep, but also more restful and restorative sleep.

No Risk of Dependence

Unlike many insomnia medications, TMS does not cause dependence or tolerance, even with prolonged use.

ADHD

Attention Deficit Hyperactivity Disorder (ADHD) affects attention, impulse control and activity. Compare the effectiveness of ADHD treatments.

Improved Symptoms of Inattention and Hyperactivity
Conventional Treatment (Medication)
35%
75%
Average rates of remission and significant improvement in symptoms (assessed by clinical scale)
Complete remission/Normalisation
Significant improvement
Transcranial Magnetic Stimulation (TMS)
14%
75%
Average remission rates and significant improvement in symptoms after neuromodulation protocol (prefrontal target, often right DLPFC)
Complete remission/Normalisation
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
60%
Percentage of patients reporting side effects (anxiety, apathy, insomnia, reduced appetite...)
Transcranial Magnetic Stimulation (TMS)
2%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
TMS (Conventional Post-Fault/Non-Response)
35%
Percentage of patients with significant improvement in symptoms after failure of ≥1 medication
Significant improvement

Important

Treatment with TMS is often used to improve the ability to concentrate and reduce impulsivity in ADHD, especially in adults. The percentages of remission with medication reflect its continuous use. Neurotherapy offers a non-systemic alternative with fewer side effects. It is crucial to discuss your specific case with a health professional.

How does our treatment work?

Transcranial Magnetic Stimulation (TMS) focuses on modulating activity in the prefrontal cortex (often the right DLPFC), a key area for executive function and attention control. This treatment can restore the balance of neural activity, improving the ability to focus and reducing hyperactivity and impulsivity without the need for daily medication.

Reducing Dependency

It allows medication to be reduced or eliminated, avoiding dependency and systemic side effects.

Cognitive Benefit

It promotes improvements in executive function, working memory and processing speed, which are essential for academic and professional success.

Smoking

Smoking is a complex addiction with high relapse rates. Compare the effectiveness of the conventional approach versus neuromodulation in the cessation process.

Cessation Rate (Continuous Abstinence)
Conventional Treatment (Pharmacological + Therapy)
20%
35%
Average abstinence rates at 6 months of treatment
Sustained Abstinence (≥6 months)
Initial abstinence (1-3 months)
Transcranial Magnetic Stimulation (TMS)
30%
55%
Average abstinence rates verified at 6 months after a complete TMS cycle (protocols involving prefrontal networks and, in deep TMS, also the insula)
Sustained Abstinence (≥6 months)
Initial abstinence (1-3 months)
Rate of side effects
Conventional Treatment (Pharmacological)
45%
Percentage of patients reporting significant side effects (e.g. mood swings, insomnia)
Transcranial Magnetic Stimulation (TMS)
1%
Percentage of patients reporting moderate side effects
Reducing Craving
TMS (Craving Reduction)
50%
Percentage of patients with a significant reduction (≥50%) in the desire to smoke after a TMS cycle
Craving reduction

Important

The success rate in smoking is closely linked to the intensity of the craving. TMS acts directly on the brain networks involved in reward and addiction. Treatment is most effective when combined with psychological counselling. It is crucial to discuss your specific case with a health professional.

How does our treatment work?

TMS targets the dorsolateral prefrontal cortex (DLPFC) and reward circuits; in deep TMS, specific protocols also include the insula. By modulating these networks, TMS reduces the desire to smoke, facilitates abstinence and reduces the long-term relapse rate, offering a non-systemic intervention.

Attacking Craving

It acts directly on the brain's addiction pathways, reducing the physical desire to smoke.

No Adverse Reactions

The treatment avoids the common systemic adverse reactions of some cessation drugs.

Post-Traumatic Stress Disorder (PTSD/TSPT)

Post-Traumatic Stress Disorder (PTSD/TSPT) is characterised by intrusive memories and hypervigilance. Compare the effectiveness of treatments.

Symptomatic Improvement (Reduction of >50%)
Conventional Treatment (Medication + Psychotherapy)
4%
30%
Average remission rates and significant symptom improvement (DSM-5) after prolonged treatment
Complete remission
Significant improvement
Transcranial Magnetic Stimulation (TMS)
12%
55%
Average remission rates and significant improvement in symptoms after neuromodulation protocol (rTMS; series ≥10-20 sessions tend to better response)
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
70%
Percentage of patients reporting side effects (e.g. drowsiness, weight gain)
Transcranial Magnetic Stimulation (TMS)
3%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
TMS (Conventional Post-Fault)
40%
Percentage of patients with significant improvement after failure of ≥1 conventional treatment
Significant improvement

Important

PTSD is characterised by changes in the brain's excitability. TMS focuses on rebalancing this excitability, especially in the areas of emotional memory and mood regulation. The ideal treatment should combine neuromodulation and trauma-focused psychological therapy. It's crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

Transcranial Magnetic Stimulation (TMS) uses magnetic pulses to modulate activity in the prefrontal cortex (often the right) and, indirectly, limbic circuits. The aim is to reduce the hyperexcitability associated with anxiety, hypervigilance and traumatic memories, promoting greater emotional regulation.

Anxiety Relief

Reduction of intrusive memories and startle response, allowing greater comfort in everyday life.

Sleep improvement

It helps restore healthy sleep patterns, often interrupted by nightmares and nocturnal hypervigilance.

Post-stroke (Neurological Recovery)

Recovery after a stroke can be a long-lasting challenge. Compare the effectiveness of conventional rehabilitation with neuromodulation approaches.

Improved Motor Function (NIHSS and Clinical Scales)
Conventional Rehabilitation (Physiotherapy/Occupational Therapy)
15%
60%
Average rates of complete motor recovery and significant improvement after standard rehabilitation (>6 months)
Complete recovery of motor function
Significant improvement in motor function
Transcranial Direct Current Stimulation (tDCS) + Rehabilitation
18%
85%
Average recovery rates and significant improvement in motor function (additional benefit when combined with rehabilitation)
Complete recovery of motor function
Significant improvement in motor function
Improving Language Function (Aphasia)
tDCS + Speech Therapy (Post Stroke)
58%
Percentage of patients with significant improvement (≥50%) in verbal comprehension/expression after combined therapy
Language improvement
Additional Side Effects Rate
Transcranial Direct Current Stimulation (tDCS)
1%
Percentage of patients reporting additional moderate side effects to rehabilitation

Important

tDCS accelerates and potentiates the gains of conventional rehabilitation by modulating brain plasticity. It is most effective when integrated into the rehabilitation programme. The aim is to reactivate the damaged area or have other areas take over the lost function. It is crucial to discuss your specific case with a healthcare professional.

How does our treatment work?

Transcranial Direct Current Stimulation (tDCS) applies a low-intensity current to increase the excitability (plasticity) of the brain hemisphere affected by the stroke and/or decrease the excitability of the unaffected hemisphere (which inhibits it). This process accelerates neuronal reorganisation, enhancing motor and language recovery when combined with therapy.

Enhances Rehabilitation

It works like a 'turbo' for neuroplasticity, making rehabilitation sessions more productive.

Time Window

Although most effective in the first few months, tDCS can induce improvements even in chronic phases (after 6 months of the stroke).

Obsessive-Compulsive Disorder (OCD)

Obsessive-compulsive disorder (OCD) imposes obsessions and rituals that cause great suffering. Compare the effectiveness of treatments.

Therapeutic Efficacy (Symptomatic Reduction >35%)
Conventional Treatment (Medication + Therapy)
15%
40%
Average rates of remission and significant improvement of symptoms (assessed by Y-BOCS scale)
Complete remission
Significant improvement
Transcranial Magnetic Stimulation (TMS)
22%
55%
Average remission rates and significant improvement in symptoms after neuromodulation protocol (usually Deep TMS)
Complete remission
Significant improvement
Rate of side effects
Conventional Treatment (Medication)
70%
Percentage of patients reporting significant side effects (e.g. drowsiness, sexual dysfunction)
Transcranial Magnetic Stimulation (TMS)
4%
Percentage of patients reporting moderate side effects
Conventional post-failure improvement
TMS (Conventional Post-Fault)
45%
Percentage of patients with significant improvement (≥35%) after failure of ≥1 conventional treatment
Significant improvement

Important

OCD is an often refractory condition. Neurotherapy offers an alternative for cases that don't respond to the maximum combination of SSRIs (medication) and CBT (cognitive-behavioural therapy). CBT acts on the fronto-striatal circuits that sustain obsessions and compulsions. It is crucial to discuss your specific case with a health professional.

How does our treatment work?

Transcranial Magnetic Stimulation (TMS) targets neural networks (anterior cingulate cortex and DLPFC) that are hyperactive in OCD and that feed the obsession-compulsion cycle. By normalising activity in these areas, TMS reduces the intensity and frequency of obsessions and the need to perform compulsive rituals, reducing the patient's suffering.

Non-Invasive and Focussed

It allows treatment focussed on dysfunctional brain networks, without the systemic effects of drugs.

Refractory cases

Highly recommended for patients who have failed treatment with medication and psychological therapy.

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Sources

  • K. Cress, MD, 2015
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  • Dunner DL, Aaronson ST, Sackeim HA, Janicak PG, Carpenter LL, Boyadjis T, Brock DG, Bonneh-Barkay D, Cook IA, Lanocha K, Solvason HB, Demitrack MA. A multisite, naturalistic, observational study of transcranial magnetic stimulation for patients with pharmacoresistant major depressive disorder: durability of benefit over a 1-year follow-up period. J Clin Psychiatry. 2014 Dec;75(12):1394-401. doi: 10.4088/JCP.13m08977. PMID: 25271871.https://pubmed.ncbi.nlm.nih.gov/25271871/
 
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  • Avery DH, Holtzheimer PE 3rd, Fawaz W, Russo J, Neumaier J, Dunner DL, Haynor DR, Claypoole KH, Wajdik C, Roy-Byrne P. A controlled study of repetitive transcranial magnetic stimulation in medication-resistant major depression. Biol Psychiatry. 2006 Jan 15;59(2):187-94. doi: 10.1016/j.biopsych.2005.07.003. Epub 2005 Sep 1. PMID: 16139808.
  • CHUC - ULS Coimbra Neuromodulation Unit

Clinical practice: ⅔ of patients show significant improvement; no significant side effects; significant total remission (exact data unknown)

  • Marilyn J. Vachè,Magnetic Stimulation for the Treatment of Major Depressive Disorder in a Severely Treatment Resistant Population- A Retrospective Private Practice Evaluation,Brain Stimulation,Volume 8, Issue 5,2015,Page e6,ISSN 1935-861X,https://doi.org/10.1016/j.brs.2015.07.021.
  • Mountain Vista, retrospective clinical analysis
  • Portuguese Journal of Psychiatry and Mental Health
  • WHO
  • NIH, USA
  • Effect of Insomnia on Repetitive Transcranial Magnetic Stimulation Treatment Outcomes for Depression, Jamie Kweon, Andrew Fukuda, Polly Gobin, Lamaan Haq, Joshua C. Brown, Linda L. CarpentermedRxiv 2023.12.06.23299444; doi: https://doi.org/10.1101/2023.12.06.23299444